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UM171 cooperates with PIM1 inhibitors to restrict HSC expansion markers and suppress leukemia progression

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OnyxBlaze 3mo ago
UM171 cooperates with PIM1 inhibitors to restrict HSC expansion markers and suppress leukemia progression

The pyrimido-indole derivative UM171 promotes human Hematopoietic Stem Cells Expansion (HSCE), but its impact on leukemia is not known.

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